Genetic Test Spots Patients at Risk From Viral Infections | 2007.08.18 |
A genetic method of identifying patients most likely to develop life-threatening complications from SARS, bird flu and other dangerous viral infections has been discovered by Canadian researchers. They analyzed blood samples from 40 people infected with SARS (severe acute respiratory syndrome) during the 2003 outbreak in Toronto. They found that patients with one kind of interferon gene-expression pattern recovered quickly, while those with another pattern became seriously ill or died, the Toronto Star reported. Interferons -- proteins produced by white blood cells -- are the body's first-line defense against viruses. SARS patients with abnormal interferon patterns didn't produce enough antibodies to fight the virus, the study found. It was published Thursday in the Journal of Virology. |